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When AsGGT2 N300 -GFP and AsGGT2 Full -GFP were expressed, weak fluorescent signals were detected both in the vacuole and cytosol (data not shown)

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Clinically relevant major bleeding was seen with 6.9% and 4.9% of patients who received lower- and higher-dose osocimab, respectively, and in 7.8% of patients who received a placebo