flow trial semaglutide kidney outcomes nejm 2024 hazard ratio 0.76 Effects of Semaglutide on Heart Failure Outcomes in Diabetes and Chronic Kidney Disease in the FLOW Trial FLOW trial Ozempic® (semaglutide injection)

10.3748/wjg.v9.i8.187710.3748/wjg.v9.i8.1874 26 ChapmanM

This is roughly equivalent to the maximum maintenance dose for diabetes management with Ozempic (2 mg weekly) but still below the maximum weight loss dose of Wegovy (2.4 mg weekly)

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One way to test for these types of effects is to compare a chronic gene deficiency with acute knockdown experiments and if the results are different, adaptive responses likely impacted the injury mechanism [153]

After all, thats how endless pharmaceutical ads have conditioned us to react (have a problem, take a pill)