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NTBI consists of potentially deleterious iron complexes in plasma, predominantly Fe 3+ -citrate or albumin complexes [14]

Lowered Physical Activity Levels Some individuals on GLP-1 weight loss drugs report feeling fatigued, which may result in decreased physical activity

This is an area that needs further research (Figure 3)

The other lesions to be considered in the differential diagnosis are smoker's melanosis, drug induced pigmentation, Addison's disease, melanotic macule, pigmented nevi junctional, intramucosal, compound, Spitz nevus, postinflammatory melanosis and oral melanoma

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