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Metabolic pathway analysis: Laboratory investigation of mechanisms linked to lipid and energy metabolism

Nov 2016;32(6):631-639

In ALS, there is an abnormal cytoplasmic aggregation of misfolded proteins, mainly DNA-binding protein 43 (TDP-43), and fused in sarcoma (FUS) (Wijesekera and Leigh 2009)

The solutions were diluted with methanol/water(1/1, v/v) to achieve concentrations of 1 g/ml of dexketoprofen for plasma analysis and 2 g/ml of dexketoprofen for fecal homogenates, urine and bile analysis

Increased glycosaminoglycan synthesis : Reviewed in Pickart & Margolina 2018, supporting structural hydration capacity