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Linus Pauling Institute Oregon State University Updated in June 2007 by: Victoria J

4.3.3 Iron homeostasis disruption Cigarette smoke (CS) perturbs systemic and cellular iron homeostasis through several interconnected mechanisms: (1) Hepcidin Upregulation: CS exposure elevates hepcidin expression, which subsequently downregulates the iron exporter ferroportin (FPN)

This method may also strip excess protein off the affinity support that is nonspecifically bound to the matrix, and this material can interfere with analysis

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Zhang F, Xiang Y, Ma Q et al (2024a) A deep insight into ferroptosis in lung disease: facts and perspectives