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doi: 10.1038/s41390-019-0608-0 26

Sermorelin is the most established of these

"MOTS-c levels in human blood decline with age and correlate with insulin sensitivity, positioning the peptide not just as a metabolic tool but as a potential biomarker of mitochondrial vitality." On the exercise side, a pivotal finding came from studies measuring endogenous MOTS-c in human subjects

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Obesity is considered to be related to increased appetite, changes in the levels of gastrointestinal hormones, increased fat mass, and disorders of satiety and satiation mechanisms (168)