This is based on animal studies that showed using the medication in pregnancy was associated with pregnancy loss as well as an increased rate of birth defects
The one or more hepatocyte growth factor mimics has or have a general structural formula R r R 2 -R 3 -NH-(CH 2 ) n -C-NH 2 1 2 3 where Rj is one of an N-acyl group, a substituted or unsubstituted phenyl, a norleucine group, and an amino acid selected from tyrosine, phenylalanine, aspartic acid, arginine, isoleucine, serine, histidine, glycine, cysteine, methionine, tryptophan, lysine norvaline, ornithine, and s-benzyl cysteine
Beyond type 2 diabetes, semaglutide is also used in weight management and the treatment of cardiovascular disorders [19]
GLP-1 reduces endoplasmic reticulum stress and apoptosis induced by hyperglycaemia and regulates mitochondrial function via stimulation of optic atrophy protein 1 [69]
For example, someone paying around $1,000 monthly for GLP-1 medication could save a few thousand dollars annually by using pre-tax HSA funds