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You must get it from food (like nuts, seeds, and leafy greens) or supplements

Erythroid mitochondrial retention triggers myeloid-dependent type I interferon in human SLE

Postmenopausal women who carried the C677T variant had a 2 to 3-fold increased risk of depression.[ref] Women with two copies of the A1298C variant were at twice the risk of major depressive disorder (MDD)