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GSH is essential for cell survival as demonstrated by observations that glutamate cysteine ligase (GCL) knockout mice die from massive apoptotic cell death [117], and that the knockdown of GCL in distinct cell types induces time-dependent apoptosis [118,119]

Enhanced immunogenicity of a human immunodeficiency virus type 1 env DNA vaccine by manipulating N-glycosylation signals

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BMC Nephrol

Genetics, pathogenesis and clinical interventions in type 1 diabetes