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Keep a symptom diary documenting when tiredness occurs, its severity, and any associated factors (meals, medication timing, activities)

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BOX 7-3 Proposed Characteristics of Congenital Melanocytic Nevi That Increase Risk for Malignancy Size Number of medium CMN Location Number of satellite nevi by 1 year of age Heterogeneity of color Rugosity Hypertrichosis Extensive nodules Adapted from Krengel, S., Scope, A., Dusza, S.W., Vonthein, R., & Marghoob, A

They also found that treatment with exenatide resulted in a marked increase in anti-inflammatory cytokines (IL-4 and IL-10) alongside a reduction in pro-inflammatory cytokines (TNF and IL-1) [65]