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Cytoplasmic NADPH generation from the CPS relies upon cytoplasmic ACLY metabolizing CoA and mitochondrial-exported citrate for the generation of oxaloacetate and acetyl-CoA

Strikingly, we found that the urothelium derived from sensitized USCs recapitulated many of the morphological differences observed previously in vivo 6 even after many passages, including smaller surface cells and decreased expression of the terminal differentiation markers Upk3a and K20 when compared with differentiated urothelium derived from nave and resolved USCs (Fig

Diabetes is defined as: Hemoglobin A1C 6.5% , or A documented history of diabetes at any time in the past

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Efficacy was predicted by early response to treatment [115]