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(2022) The global burden of cardiovascular diseases and risk, J

Benefits: Improves circadian rhythm by promoting the delta rhythm, achieved in Stage 4 of sleep (the stage when Growth Hormone is made) Antioxidant effect in the brain via increases in glutathione peroxidase and superoxide dismutase Increased alertness, improved stress tolerance, and coping behavior during awake cycles Restoration of slow-wave sleep in Cushings Syndrome Possible anticonvulsant action by increasing the threshold to NMDA- and picrotoxin-induced convulsions Increase in testosterone levels when treating with DSIP alone (100-200 point increases have been observed) Side Effects: Potential to disrupt sleep

Sinclair tweeted in 2020 that he takes coQ10 nightly because he takes a statin

However, they may also result in increased sensitivity to chemotherapy, leading to better treatment outcomes PubMed Central

8 , e3009 (2017)