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The authors performed ChIP-Seq using expression constructs that yield AR DBD domains that are linked to functional domains that convey transcriptional activation or repression, both in benign and malignant prostate cells and organoids

Phytomedicine 14(12):799805 Pappa T, A

Simultaneously, released Cu 2+ causes redox reaction with the intracellular overexpressed GSH, and subsequently produces Cu + for initiation of Fenton-like reactions, resulting in the production of OH and robust anticancer therapy

Each signature was queried against the CMap using the algorithm described by Lamb et al .[13]

Therefore, the use of KD in individuals with PD can raise concerns, as their nutritional status is a significant factor affecting lifespan, and people with PD are already at a high risk of malnutrition