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Subfamilies and isoforms can be categorized based on the sequence similarity, domain architecture, quaternary structure, enzymatic activity, ironsulfur cluster binding and the number of active site cysteine residues 1,2,3,4,5

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Research confirms no noticeable cell loss in cultures of non-senescent chondrocytes, validating selective targeting capabilities

In breast cancer models, chloroquine-loaded nanoparticles combined with PD-L1 antibodies and chemotherapeutics induced apoptosis and reversed immune-cold tumor microenvironments (167)