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In neuronal PC12 cells, these strong experiments reveal that HTyr suppresses the aberrant aggregation of -synuclein, a protein that plays a key role in synucleinopathies
Barkmeier AJ, Herrin J, Swarna KS, et al
Its substrates also include pituitary adenylate cyclaseactivating polypeptides, insulinlike growth factor1, peptide YY, substance P, neuropeptide Y, gastrinreleasing polypeptides, and several chemokines, indicating its role in additional homeostatic functions, such as neurogenic inflammation, blood pressure control, and immune regulation [41]
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