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Chronic health conditions: Diabetes, heart disease, obesity, depression, and autoimmune disorders can all lower energy and sexual function, creating barriers to a healthy sex life

10.20944/preprints202105.0182.v1 Preprints

Personal preference: weekly injection, daily tablet, stimulant versus nonstimulant treatment and willingness to follow dose-escalation instructions

Significant results typically emerge by weeks 12-16 as maintenance doses are reached

Targeting the Trem2-APOE pathway can restore the homeostatic signature of microglia in ALS and AD mouse models, potentially preventing neuronal loss and promote tolerogenic T-cell response (Krasemann et al., 2017)