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To enable clinical application, further high-quality preclinical studies and well-designed clinical trials are necessary to validate its efficacy and clarify the underlying mechanisms of action

Since patients with cirrhosis often manifest a deficiency of BCAAs compare to aromatic amino acids (which worsen hepatic encephalopathy)

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10.1515/REVNEURO.2007.18.6.439 41 OancaG.StareJ.MavriJ

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