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Quality matters significantly here

Dose and rate matter (e.g., magnesium given too quickly may cause flushing or low blood pressure)

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doi: 10.3389/fmolb.2023.1170181 Received 20 February 2023 Accepted 28 March 2023 Published 07 April 2023 Volume 10 - 2023 Edited by Catalina Dirney Alba Soto, University of Buenos Aires, Argentina Reviewed by Jacek Mokrosinski, Novo Nordisk Research Center Indianapolis, United States Brian Hudson, University of Glasgow, United Kingdom Updates Copyright 2023 Austin and Tomas

and 416.310(d), respectively, to include extensions of time as a form of relief and to further clarify the policy