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Studies had identified that organic cation transporter 2 (OCT2, SLC22A2) mediates TMAO uptake into renal proximal tubular cells and that multiple transporter of the ATP-binding cassette (ABC) family, including ABCG2 (BCRP) and ABCB1 (MDR1), are capable of TMAO efflux (Miyake et al., 2017

Confirmed as mild and low-irritating product from in irritation test that can be used on sensitive skin types

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Month 1: Mild nausea, decreased appetite, fatigue, and digestive changes are common as your body adapts to the starting dose

Mild side effects such as temporary bruising, headache, or nausea may occur but typically resolve quickly