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[1] [2] Unlike phentermine's central nervous system stimulation, tirzepatide works through multiple mechanisms: it enhances insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and reduces appetite through central pathways

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[DOI] [PMC free article] [PubMed] [Google Scholar] 76.Garvey W.T., Batterham R.L., Bhatta M., Buscemi S., Christensen L.N., Frias J.P., Jdar E., Kandler K., Rigas G., Wadden T.A., et al

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