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According to the results, overactivity of A2AR leads to synaptic and memory dysfunction in early AD

Corilagin, an ellagitannin that represents a derivative of ellagic acid, inhibited NADPH oxidase 2 (NOX2) which increases sleep deprivation-induced oxidative stress

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Compared to anti-inflammatory counterparts, pro-inflammatory microglia performed increased resistance to ferroptosis, likely because of an elevated NRF2 expression and a greater abundance of iNOS/nitric oxide