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Dupr y Viraben 6 agrupan bajo la denominacin de enfermedad de Laugier un conjunto de entidades con diversas denominaciones segn la localizacin topogrfica: mcula melantica labial, pigmentacin melnica adquirida del labio inferior, mcula melantica oral, lentigo labial solitario, lentiginosis genital, lentiginosis del pene y de vulva, lentigo atpico del pene y melanosis del pene

These cardiovascular characterisation studies established that MT-IIs haemodynamic effects are mechanistically related to its central MC3R/MC4R activation rather than to peripheral melanocortin receptor engagement