Preclinical work shows CBD can be protective in early-psychosis models, but only during specific developmental windows
In particular, THR- activation is linked to important metabolic benefits in the liver, as it can reduce cholesterol and triglyceride levels, stimulate bile acid synthesis, and promote fat oxidation
Ethics declarations Ethics Approval Considering the nature of this review, which synthesizes data from previously published studies, ethical approval was not deemed necessary
It increases GABA, serotonin, and dopamine to affect mood regulation
Genetics can also play a role, and for an individual approach we often consider variations to gene SNPs such as SLC17A7 and APOE (16, 17), that can affect how well a child calms inflammation, detoxifies, produces and clears key neurotransmitters