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Haigis, K

This application note demonstrates how MMS can be used to quantify peptide concentrations and determine structural differences between unmodified GLP-1 and the commercial GLP-1 analogues in different buffer systems, highlighting the advantages of MMS as a biophysical tool for the development of peptide therapeutics

Recently, a new DON prodrug, DRP-104 (sirpiglenastat) was developed, which carries isopropyl ester and acetylated tryptophan on the C-terminal and N-terminal of DON (Rais et al., 2022)

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B12 deficiency can have similar symptoms, as well as neurological ones, such as numbness and tingling in the hands or feet