They tried a few tricks: DPP-4-resistant versions: tweaking the GLP-1 molecule so DPP-4 cant see where to cut it Fatty acid tails: causing the GLP-1 to latch onto albumin in your blood, hiding from DPP-4 Encapsulation: wrapping the molecule in protective coatings so it survives longer before being exposed to enzymes These hacks meant the drug could hang out in the bloodstream for hours, or even days, instead of minutes
Usage and visibility of GLP-1s have been increasing, especially among younger generations
References Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al
Image credits: beyonce "Dark hair creates a frame that highlights the skin, while blonde or ash tones can soften the contrast and make the skin appear lighter," she said, looking at Beyonc's pictures
Companys, J