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The votes are nonbinding, and the committee broke with the agency's own scientists, who said the drugs have not been adequately studied in people

Considering its potential impact on ghrelin receptors, Ipamorelin may enhance appetite, possibly leading to weight gain

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Contact your GP if green stools persist beyond one week without dietary explanation, or immediately if you notice black tarry stools, bright red blood, pale clay-coloured stools, severe abdominal pain, or signs of dehydration

The 2025 NEJM trial comparing tirzepatide directly against semaglutide showed 20.2% versus 13.7% weight loss over the same treatment period