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Biochemistry 2003

Ascorbic Acid is also needed for: Carnitine synthesis Tyrosine synthesis and catabolism Serotonin (neurotransmitter) synthesis Other hormone and neurotransmitter synthesis6 The figure below shows how ascorbic acid is needed for dopamine hydroxylase, which ultimately produces the hormone epinephrine

Post-translational modifications can lead to significant changes in protein structure, affecting both the physical arrangement of amino acids and the biochemical activities within biological systems

A further increase in the level of oxidative stress could ultimately trigger a cytotoxic response originating in the mitochondria and lead to cellular apoptosis or necrosis (Figure 2)

Revel JP, Ball EG