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The proposed mechanism involves direct interaction between the AEDG sequence and histones H1/3 and H1/6 a form of epigenetic regulation in which the peptide modulates chromatin accessibility at specific gene loci, thereby influencing transcriptional activity without altering the underlying DNA sequence (9)

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As we celebrate America's 250th birthday, we're also celebrating the researchers, scientists, and innovators who continue asking the next generation of questions

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Substances below the dotted line penetrate much less than expected from their lipophilicity or are extruded via the P-glycoprotein efflux pump