In this case, 5-h-fasted mice were intraperitoneally administered with 0.75 U of insulin (Sigma-Aldrich, MO, USA) per kg body weight, and blood glucose concentrations were determined before (0) and at 15, 30, 60, and 120 min after insulin injection
Metabolomics is often considered as a powerful technology to analyze the changes of concentration profiles of low-molecular-weight metabolites in biological system, and can provide fundamental insights into perturbed metabolic pathways in different diseases, including in RA
Endocrine 68 , 7180 (2020)
The authors proposed peripheral mechanisms such as reduced genital blood flow and central modulation of dopamine and noradrenaline in brain regions regulating reward and arousal
Within the NSCLC tumor microenvironment, TLCA showed synergistic effects with anti-PD-1 therapy, highlighting the potential of BA-mediated immunomodulation to improve immunotherapy outcomes in specific cancer types (115)