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9 When the coagulation system is persistently activated, blood flow efficiency decreases

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Chronic Fatigue: Persistent tiredness and lack of energy can be an early indicator

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Alzheimers disease (AD), a neurological disorder of memory loss and changes in behaviour, is associated with the accumulation of amyloid protein plaques because of the intracellular neurofibrillary tangled (NFT) aggregation produced by abnormally hyper phosphorylated tau () protein