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Safety analysis set: all randomised participants who were exposed to at least one dose of study product 1G first generation, 2G second generation, AE adverse event, E number of events, n number of participants, PT preferred term, SAE serious adverse event, SOC system organ class, TEAE treatment-emergent adverse event Group 1 Overall, 186 (83.8%) of 222 participants reported a total of 904 TEAEs (Table 4)

One mechanism involves regulation of invariant natural killer T cells (iNKT cells) in psoriatic plaques, plus AMPK activation that reduces keratinocyte proliferation

Clinical trials have demonstrated its remarkable ability to reduce body weight by enhancing satiety and reducing calorie intake