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In response to oxidative agents, inflammation, infections or neurodegeneration, astrocytes undergo profound changes in morphology, gene expression and functiona phenomenon known as astrocyte state transition

Trials show percent bodyweight reductions that often improve blood pressure and glucose control for patients with related conditions

In the United States, obesity prevalence among children and adolescents aged 2 to 19 years increased from 17.7% in 20112012 to 21.5% in 20172020, underscoring the accelerating nature of this epidemic