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Several clinical studies have found that GSH consumption exists in the blood of patients with myocardial infarction and the left ventricle of patients with heart failure [8, 38, 39]

*Correspondence: Youxin Chen, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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To maintain enough H 2 O levels for hormone production without causing oxidative damage, GPX activity is necessary [16]