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When dehydration develops, urine may become more concentrated, which can occasionally irritate the bladder or increase urinary discomfort

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SHMT1-mediated metabolism also influences the ability of tumor cells to synthesize crucial lipids, like sialic acid N-acetylneuraminic acid, which supports the release of cytokines (IL-6 and IL-8) involved in ovarian cancer cells proliferation and migration in mouse models [119]

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This helps slow down gastric emptyingthe speed at which food leaves your stomachand communicates a sense of satiety to the brain