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The data showed dose-response relationships for both the benefits and the side effects (i.e., the higher the dose, the higher the efficacy and the greater the rate of bothersome side effects)

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As a Th2 effector, IL-31 correlates with itch severity and signals via IL-31 receptor alpha (IL-31RA)/Oncostatin M receptor beta (OSMR) receptors on sensory nerves to release calcitonin gene-related peptide and drive neurogenic inflammation (Fassett et al., 2023)

Studies have demonstrated that glutathione lessens cell damage in alcoholic and non-alcoholic fatty liver diseases