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If urinary symptoms are new, worsening, or associated with pain, fever or skin irritation, seek medical advice

Difficulties arising from potential immunogenicity, large molecular weight, need for carriers for their delivery and instability in vivo are well recognized [188]

Skin conditions at the injection site Never inject into skin that shows signs of damage or disease

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Pedrosa L, Esposito F, Thomson TM, Maurel J (2019) The tumor microenvironment in colorectal cancer therapy