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Although the precise molecular mechanisms of the NLRP3 inflammasome activation remain to be fully elucidated, reactive oxygen species (ROS) are widely regarded as essential for NLRP3 inflammasome activation (111)

As we said earlier, ROS are important in the development of AMD [2,3,4,8]

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Senescent Cell Clearance Evidence: Animal + In Vitro | Quality: Strong (for preclinical) The core benefit of FOXO4-DRI is selective elimination of senescent cells

Despite the 12% global prevalence [3], BD is considered one of the leading causes of disability worldwide [4], especially with its early onset in adolescence or early adulthood [5]