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In addition to energy production, mitochondria perform multiple other functions including Ca 2+ homeostasis [86, 87], generation of ROS [88], regulation of apoptosis [89], activation of endoplasmic reticulum-stress response [90], as well as other far-ranging sequelae of mitochondrial dysfunction [91]

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However, the upstream regulators and the underlying mechanisms that govern these oligomeric states require further investigation

Ageing Research Reviews, 100 , 102406