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Emery RL, Benno MT, Salk RH, Kolko RP, Levine MD

Sjberg KA, et al

BECN1 inhibition decreases GCs autophagy and lowers low-density lipoprotein-induced progesterone synthesis ( GCs from EMS patients exhibited lower expression of not just 3-HSD, but also CYP19, as well as impaired ability to release inhibin B and estrogen ( 4.4 EMS influences mitochondrial energy metabolism in GCs Because GCs are the nanny cells that feed the oocyte, mitochondria play a vital role in energy metabolism

In the vessel wall, impairment of lipid metabolism could cause pathologic lipids accumulation (52)

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