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Retatrutide is a novel triple-acting peptide agonist that simultaneously targets three key hormonal pathways: GIP (glucose-dependent insulinotropic polypeptide), GLP-1 (glucagon-like peptide-1), and glucagon receptors

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The role for GSTs in the detoxification of the reactive metabolite2-ABT-S-oxide (M1) of zileuton, an agent which targets the leukotriene pathway through inhibition of 5-lipoxygenase (5-LO), has been investigated [55]