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(2014, Journal of Neurological Sciences) showed that systemic T4 use improved neurological function and promoted oligodendrocyte survival and remyelination in experimental autoimmune encephalomyelitis (EAE) models

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When chronic diseases such as rheumatoid arthritis, CKD, cancer, or infections affect the production of red cells or the red cell maturation process called erythropoiesis, and lead to ways the body metabolizes iron through hepcidin-mediated processes getting out of control