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However, the heterogeneity in MASLD etiology has made it challenging to develop a preclinical animal model that accurately reflects MASLD progression in humans

What confused me most was the contradiction, because even though I lost weight and my jawline looked sharper, my stomach looked as if I had just finished a Thanksgiving meal

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A systematic review and meta-analysis published in 2025 suggested GLP-1s were not cost-effective in treating obesity without diabetes