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PMID: 38760474, PMCID: PMC11101464, DOI: 10.1038/s41746-024-01120-w
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doi: 10.1186/s13062-022-00318-w 191 TryggestadAMAAxcronaKAxcronaUBigalkeIBrennhovdBInderbergEMet al
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In subjects with altered glucose tolerance, two LF gene polymorphisms (LF rs1126477 and rs1126478) were associated with HDL-C and TG levels ( Exogenous supplementation of LF could also improve energy metabolism ( 3 Mechanisms of lactoferrin alleviating the metabolic syndrome 3.1 Anti-inflammatory effects of lactoferrin improve insulin resistance Inflammation is an important cause of the development of insulin resistance ( Figure 1 ) ( Figure 1 In T2DM mice, LF ameliorates pancreatic dysfunction by reducing inflammatory responses through regulating the PI3K/AKT signaling pathway
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