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Note: No significant changes in bone turnover markers (osteocalcin and bone-specific alkaline phosphatase) were observed in studies (PMID: 10373343, PMID: 10828840)

However, this Th1/Th2 dichotomy was not able to explain the multitude of immune responses in pregnancy among them is the fact that some Th1 cytokines are necessary in some aspects of pregnancy [81] and it did not explain the suppression of autoantibodies, including thyroid autoantibodies

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Selenium: its role as antioxidant in human health

doi: 10.1167/iovs.08-1856 282 YefimovaMGJeannyJCKellerNSergeantCGuillonneauXBeaumontCet al