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It is cost-effective and a viable long-term solution without the harmful side effects of opioids or other pain medications

In addition to RIDD, IRE1 also induces non-conventional splicing and activation of XBP1, a major transcription factor regulating ER homeostasis 10,66,67,68,69

The experimental group treated with L.plantarum NCU116 showed increased expression of PPAR , PPAR , PPAR , PGC1 and CPT1 , leading to effective reduction of hepatic fat accumulation (Li et al., 2014)

9.5 Other GSH-responsive therapeutic strategies Modalities GSH-activated nanomedicines were also developed for other therapies, including photothermal therapy

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