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Comparator Selection: Full-length hGH (to demonstrate receptor-independent effects) -adrenergic agonists (to show distinct mechanism) Vehicle control 4

Future work is needed to directly compare between phytoncides and existing hypnotics in terms of the side-effects

doi:10.1016/j.diabet.2023.101470 108

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In the recently published SELECT trial results, for example, semaglutide (marketed by Novo Nordisk as Wegovy for weight loss and Ozempic for type 2 diabetes) demonstrated a 20% risk reduction of heart attacks and strokes in overweight and obese individuals without diabetes and with cardiovascular disease, establishing it as a cardiovascular diseasemodifying medication in people without type 2 diabetes