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A newer compound, N-acetyl-L-cysteine ethyl ester (NACET) may be more effective as it can readily cross the blood-brain barrier and protect cells from oxidative stress

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The hydrolytic cleavage of its 6-nitro-2,3-dihydroimidazo [2,1-b] oxazole moiety generates M1, which undergoes further transformations involving hydroxylation and oxidation, mediated largely by CYP3A4 (Szumowski and Lynch, 2015