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In a foundational 2009 study, Li and colleagues found that GLP-1R stimulation preserved both cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism [5]

This offers a clear, mechanistic explanation for why so many dysautonomia patients report improved orthostatic tolerance and reduced tachycardia when incorporating mitochondrial shuttles into their daily treatment protocols

Several other clinical medications including anti-adrenergic (such as salbutamol, salmeterol, and formoterol), 101 HIV protease inhibitors, 102,103 atypical antipsychotics 104 and some exogenous insulin 105 that may improve IR because of the disordered insulin signaling

This treatment is especially beneficial for those dealing with related conditions such as insulin resistance or prediabetes, as it helps regulate blood sugar levels