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In the present study using obese mice fed HFD for 5 weeks or longer, food intake in LP (7:3019:30) was approximately doubled, whereas that in dark period (DP, 19:307:30) unaltered, exhibiting LP-specific hyperphagia accompanied by daily hyperphagia (Figs

Nevertheless, there is no doubt that GLP-1 interacts with vagal afferent neurons and the arcuate nucleus of the hypothalamus, critical components of the gut-brain axis that connect peripheral metabolic signals to the central nervous system [10]

By disrupting the interaction between p53 and FOXO4, the FOXO4-DRI peptide induces apoptosis (programmed cell death) in senescent cells without harming healthy ones

This review presents the biological and chemical characteristics of TMAO, and the process of TMAO produced by gut microbiota

By mimicking the natural hormone GLP-1, these medications offer a multifaceted approach to managing blood sugar, reducing appetite, promoting weight loss, and even improving cardiovascular health