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Compounds such as phenolics, flavonoids, and carotenoids have been shown to mitigate oxidative damage and reduce the risk of chronic diseases

The molecular mechanisms by which TMAO exacerbates renal insufficiency, include the activation of inflammatory pathways, induction of oxidative stress, SMAD signaling, and impairment of endothelial cell function [12, 38]

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Insulin-like growth factor signaling in Alzheimers disease: pathophysiology and therapeutic strategies